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Excedrin Migraine


Excedrin Migraine is a non prescription, over the counter drug and was first used to treat patients with moderate to severe migraines. Migraine is described as a recurrent headache that is often associated with other symptoms such as dizziness, sick stomach and fever. The release of chemicals from nerve fibers causes blood vessel enlargement resulting in pain, inflammation and artery enlargement. As blood vessels enlarge, the pain intensifies. People who experiences migraine are more often sensitive to light, sound or smell.

Although migraine headaches may present with other symptoms, Excedrin Migraine is only indicated to treat the pain associated with migraine. Furthermore, compared to other medications, it is frequently recommended by doctors because it is inexpensive, proven effective, safe and provides lasting relief and effectiveness. In just 30 minutes after taking one dose of Excedrin Migraine patients experiencing migraine feel a noticeable reduction in pain. Usually it is recommended to take two tablet dose of Excedrin Migraine, taken at 6 hour interval as needed. You may check package labelling information for the proper dosage that is recommended for treating migraine.

Excedrin Migraine is available in 3 forms: the Geltabs, Tablets, and Caplets. Whichever you prefer it is important that you use this medicine according to label instructions. However, it’s still best to consult your doctor for diagnosis and treatment options if symptoms continue to worsen.

Excedrin migraine ingredients

It has 3 active primary ingredients. These are Acetaminophen, Aspirin and Caffeine.  Excedrin Migraine

Acetaminophen: Excedrin Migraine contains 250 mg of Acetaminophen. It is an analgesic (pain reliever) and antipyretic (fever reducer). It is not considered an NSAID as its anti-inflammatory activity is weak. To reduce pain, Acetaminophen elevates pain threshold by inhibiting the chemical signals for pain. To reduce fever, Acetaminophen promotes heat loss by its action on heat regulating centre of the brain. Through this it aids in resetting the hypothalamic thermostat.

Aspirin: Excedrin Migraine contains 250 mg of Aspirin. Aspirin is a salicylate drug as well as an analgesic, antipyretic and anti-inflammatory. Aspirin reduces body chemicals that cause the symptoms of pain, inflammation and fever. Aspirin has been used to prevent blood clot formation resulting in improved blood circulation.

Caffeine: Excedrin Migraine contains 65 mg of Caffeine. Caffeine is a central nervous system stimulant wherein it increases wakefulness, restores alertness, increases focus and improves body coordination. Also it acts as a metabolic stimulant where it increases individual’s metabolic rate. Aside from relieving pain, it also serves as a muscle relaxant. During relaxation it dilates the blood vessels thus allowing proper blood flow, alleviating the headache. However, the effect of caffeine may differ from person to person as it depends on an individual’s body size and level of tolerance.

Inactive ingredients: Inactive ingredients are components which do not directly help to achieve the relief of symptoms. They have no effect on a drug’s absorption or metabolism. These are substances that aid or support the active ingredients in terms of color, stability, preservatives, delivery and binding of the drug together. However, not all inactive ingredients are safe. If in case you have an allergic reaction to these substances it is best to consult your doctor.

Inactive Ingredients are: Benzoic acid, Carnauba wax, FD&C blue #1, Hydroxypropyl cellulose, Hypromellose, Light mineral oil, Microcrystalline cellulose, Polysorbate 20, Povidone, Propylene glycol, Simethicone emulsion, Sorbitan monolaurate, Stearic acid and Titanium dioxide.

Excedrin migraine dosage

Recommended dose for adults who are 18 years of age or older is 2 tablets daily every 6 hours as needed. You should not take more than 2 tablets in 24 hours and a maximum 8 tablets per day for 2 days. The dosage for children who are less than 18 years of age should be consulted by a physician.

Overdose of Excedrin Migraine: It is important that you use this drug exactly as directed on the packaging label instructions or as advised by your doctor. If you suspect overdose of this drug seek immediate medical attention. An overdose causes tinnitus, headache, dizziness, hallucination, diarrhea, bradycardia, tachycardia and seizures. On the other hand Acetaminophen overdose is also common. The symptoms are: decreased appetite, nausea, vomiting, and pain in stomach, increased sweating, confusion and weakness. Later symptoms include: upper stomach pain, dark urine, extreme fatigue, irregular heartbeat, low blood pressure and yellowing of skin or eyes.

Excedrin migraine side effects

All medications have known side effects. Though the drug is proven safe and effective it is still important that you take necessary precautions when taking it. Always check the package label for proper dosage so as to minimize the possible side effects and complications. It is always best to consult your doctor for proper diagnosis and treatment in case side effects continue to persist or if condition worsens.

Less Serious Side Effects are: Cramps, severe vomiting and nausea, stomach pain, diarrhea, weakness or fainting, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes), sleeping problem, fever lasting longer than 3 days, pain lasting longer than 10 days, and tinnitus.

More Serious Side Effects of Excedrin Migraine are: Abdominal swelling, Red or white pigmentation on skin (though it may be reversible), severe irregular internal bleeding, black, bloody, clay-colored stools and coughing up blood.