NSAIDs ListNSAID list

Aspirin Allergy


Aspirin allergy are symptoms that can occur, in rare cases, to people who use this drug. These symptoms can be mild, but depending on the person and the disease on which it suffers, they can get worse. Known for over 3500 years salicylates  have been used in ancient times in various forms by Egyptians, Greeks, Chinese or Native Americans for their anti-inflammatory properties. Rediscovered in the late 19th century, this drug was registered by pharmaceutical company Bayer in 1899, under the name Aspirin. Three years later, in 1902 it was reported the first Aspirin allergy, and that was an anaphylactic reaction, 10 years later the first bronchospasm, and shortly after that the first death produced by this anti-inflammatory product.

What are the symptoms of an Aspirin allergy ?

This drug is considered by many our rescue when we are faced with mild pains, and at first sight it appears to be an absolutely harmless drug, but in some cases by using it it can cause an Aspirin allergy. It is true that there are rare cases where people are allergic to Aspirin, but when this happens , the situation is not pleasant. For example, Aspirin can cause severe asthma attacks to those who suffer from this disease but also to the people who have problems with sinuses. Other symptoms of Aspirin allergy are:

  • itchy skin
  • hives                                                                                                               Aspirin allergy
  • swollen face, tongue or lips
  • red eyes
  • cough, shortness of breath
  • nasal secretions
  • stomach pain
  • anaphylaxis – a life-threatening reaction

If you have experienced such Aspirin side effects, it would be best to avoid this medicine because it means you are allergic, and next time those symptoms may worsen.

In 1922 is described the association between hypersensitivity to Aspirin, asthma and nasal polyposis known as Widal-Samter’s triad. Hypersensitivity to Aspirin is seen as a rate between 0,5-2,5 % of the population, and is more common in women and children. Patients who are allergic to Aspirin may be allergic to all NSAIDs that inhibit COX-1(Ibuprofen, Naproxen etc.)

Aspirin and other NSAIDs can cause or increase skin rashes in 20-40% of patients with chronic urticaria. This Aspirin allergy reaction can occur between 15 minutes and 24 hours after ingestion of the tablet.

Once diagnosed with Aspirin allergy and other NSAIDs, patient education is crucial. They should have lists of drugs allowed and contraindicated especially for situations which require the annihilation of acute pain. You need to check the label before buying any medicine because aspirin composition is found in many drugs. In any case is good to know that only in rare cases an Aspirin allergy can cause a deadly disease.